Neuropathology and Genetics of Dementia (Advances in Experimental Medicine and Biology Volume 487)

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Management number 233413758 Release Date 2026/06/27 List Price US$53.88 Model Number 233413758
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these "tauopathies" are reviewed by Delacourte. Therecentdiscoverythatmutationsofthetaugenearecausativeforfamilial formsoffrontotemporaldementiaandParkinsonism(FTDP-17)broughtthe "taupathway"and the"tauopathies"tothecentrestage.Thisextraordinary breakthroughwillbecoveredbySpillantiniandGoedert.Thereisincreasing evidence that argyrophilic grain disease is much more frequent in older patients than previously thought. Tolnay et al. are reviewing recent contributionstothepathologyofthislate-onsetdementingdisorderinwhich ofamyloidbetadeposits,isalmost taupathology,inthealmosttotalabsence exclusivelyrestricted to the limbic lobe and the amygdala. Schultzet al. report an intriguing age-related progression of neuronal and glial tau pathologyinbaboonsthusrenderingthe baboonapotentialprimatemodel forage-relatedhuman"tauopathies". Gotzetal. introducetransgenicmice expressingmutated human tau as valuable animal models for reproducing formationofneuro-andglialfibrillarylesions. Read more

ISBN10 0306465582
ISBN13 978-0306465581
Edition 2001st
Language English
Publisher Kluwer Academic
Dimensions 6.75 x 1 x 10.25 inches
Item Weight 1.6 pounds
Print length 255 pages
Part of series Advances in Experimental Medicine and Biology
Publication date May 31, 2001

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